RNA Details
Disease Name
diabetic cardiomyopathy
Tissue
heart
RNA Symbol
mir-203
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
NA
Target
PIK3CA
Pathway
PI3K-AKT SIGNALING PATHWAY
PubMed ID
Title
Up-regulation of microRNA-203 inhibits myocardial fibrosis and oxidative stress in mice with diabetic cardiomyopathy through the inhibition of PI3K/Akt signaling pathway via PIK3CA
Year
2019
Function
Overexpression of miR-203 may function as a cardioprotective regulator in diabetes cardiomyopathy (DCM) by targeting PIK3CA via inactivation of pi3k/Akt signaling pathway.